If we wish to draw philosophical conclusions about our own existence, our significance, and the significance of the universe itself, our conclusions should be based on empirical knowledge. A truly open mind means forcing our imaginations to conform to the evidence of reality, and not vice versa, whether or not we like the implications.
Of course, supernatural acts are what miracles are all about. They are, after all, precisely those things that circumvent the laws of nature. A god who can create the laws of nature can presumably also circumvent them at will. Although why they would have been circumvented so liberally thousands of years ago, before the invention of modern communication instruments that could have recorded them, and not today, is still something to wonder about.
In 5 billion years, the expansion of the universe will have progressed to the point where all other galaxies will have receded beyond detection. Indeed, they will be receding faster than the speed of light, so detection will be impossible. Future civilizations will discover science and all its laws, and never know about other galaxies or the cosmic background radiation. They will inevitably come to the wrong conclusion about the universe... We live in a special time, the only time, where we can observationally verify that we live in a special time.
Now, almost one hundred years later, it is difficult to fully appreciate how much our picture of the universe has changed in the span of a single human lifetime. As far as the scientific community in 1917 was concerned, the universe was static and eternal, and consisted of a one single galaxy, our Milky Way, surrounded by vast, infinite, dark, and empty space. This is, after all, what you would guess by looking up at the night sky with your eyes, or with a small telescope, and at the time there was little reason to suspect otherwise.
A universe without purpose should neither depress us nor suggest that our lives are purposeless. Through an awe-inspiring cosmic history we find ourselves on this remote planet in a remote corner of the universe, endowed with intelligence and self-awareness. We should not despair, but should humbly rejoice in making the most of these gifts, and celebrate our brief moment in the sun.