Our findings provide a rational explanation for why H 5 N 1 viruses rarely infect and spread from human to human, although they can replicate efficiently in the lungs.
Yoshihiro Kawaoka
It is a mixture. Within the mixture we found virus that is highly, highly resistant. When you look at the virus as a whole, it is partially resistant.
found
By reducing the number of plasmids, we increase the efficiency of virus production.
efficiency
Application of the new system may be especially advantageous in situations of outbreaks of highly pathogenic avian influenza viruses.
system
Patient 1 had not had any known direct contact with poultry, but had cared for her 21-year-old brother (patient 2) while he had a documented H5N1 virus infection
brother
We don't know how many more mutations are required. But at this point, we still have some time.
time
human explanation rational
Only one case, and whether that condition was something unique we don't know.
unique
We don't know how frequently this kind of mutation can appear
kind
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